EXHALION is designed to facilitate Standard Operational Procedures for online breath analysis with SUPER SESI- HRMS. The dynamics of the lung, and its impact on the emission of different species, is extremely complex, and not known in detail. It is a consensus among the scientific breath research community, that standardizing the exhalation conditions is an essential step to eliminate sources of potential confounding factors. EXHALION links the new MS data with the well-established capnography knowledge. For instance, the CO2 profile allows distinguishing different lung fractions and their metabolites.